In addition, the WBC count>10 × 10<sup>9</sup>/L, lymphocyte count<1 × 10<sup>9</sup>/L, PCT>0.5 ng/mL, and CRP>10 mg/L were risk factors for disease progression in patients with COVID-19 (WBC count>10 × 10<sup>9</sup>/L: OR = 2.92, 95% CI: 1.96-4.35; lymphocyte count<1 × 10<sup>9</sup>/L: OR = 4.97, 95% CI: 3.53-6.99; PCT>0.5 ng/mL: OR = 6.33, 95% CI: 3.97-10.10; CRP>10 mg/L: OR = 3.51, 95% CI: 2.38-5.16). This evidence concerns the gene CRP and COVID-19.