Based on data for 178 cancer and four normal samples present in TCGA, the expression of CASC8 was found to be significantly upregulated in PAAD [FPKM, fold change = 8.71, P = 0.0014, false discovery rate (FDR) = 0.04] (Figure 1). This evidence concerns the gene CASC8 and pancreatic adenocarcinoma.