Age, pre-existing conditions (cardiac disease, hypertension, and more than two comorbidities), and 1st Laboratory detection (WBC, NEU, LYM%, NEU%, NLR, FIB, CRP, TBIL, ALB, GRF, CK-MB, Myoglobin, and Troponin) were identified as the predictors of the severity of disease by univariate analysis. The gene discussed is GHRH; the disease is heart disorder.