Some elements of the immune environment can promote anticancer immunity, including conventional CD8+ cytotoxic and CD4+ helper T cells, and unconventional lymphocyte subsets with potent tumour-killing ability, such as natural killer (NK) cells (52), gamma-delta (γδ) T cells (53), and mucosa associated invariant T (MAIT) cells (54). Here, CD8A is linked to neoplasm.