Moreover, they showed that in COVID-19 patients' sera with the need for intensive care unit (ICU)admission, there was a high concentration of Granulocyte-colony stimulating factor (G-CSF), C-X-C Motif Chemokine Ligand 10 (CXCL10), Monocyte chemoattractant protein 1 (MCP1), Macrophage inflammatory protein 1 A (MIP1A), and TNF-α. This evidence concerns the gene CSF3 and COVID-19.