In the transcriptome of our EVs, we found also MIR490 that seems to have the role of tumor suppressor in lung cancer cells A549 and ovarian cancer by blocking the transcription of CCND1 and CDK1 respectively, two important genes involved in cell cycle progression (Gu et al., 2014; Chen et al., 2015). The gene discussed is CCND1; the disease is ovarian cancer.