These genes were CEP55, DTL, FANCI, HMMR, KIF15, MCM6, MKI67, NCAPG2, NEK2, RACGAP1, RRM2, TOP2A, UBE2C, and ZWILCH. One miRNA (hsa-mir-4437) and four genes (FANCI, KIF15, NCAPG2, and ZWILCH) have not yet been confirmed to be associated with colon cancer in previous experiments and calculations. The gene discussed is TOP2A; the disease is malignant colon neoplasm.