ZEB1 and colonic neoplasm: Studies show that down-regulation of miR-708 expression could inhibit the progress of colon cancer cells by targeting the tumor promoter zinc finger E-box binding homeobox 1 (ZEB1), and overexpressed miR-155 could promote the proliferation of cancer cells by targeting the tumor suppressor cbl proto-oncogene (CBL) (Yu et al., 2017; Sun et al., 2019).