Autoimmunity was also prevalent among patients with Wiskott–Aldrich Syndrome (two out of three patients), STAT5b deficiency (two out of two patients), NF-kB2 deficiency (two out of two patients), Fas and FasL deficiency (three out of four patients), LRBA deficiency (three out of three patients), APECED (three out of three patients), IL-10 deficiency (four out of four patients), and complement C4 deficiency (four out of five patients; Table 4). This evidence concerns the gene LRBA and hyperinsulinemic hypoglycemia, familial, 4.