The largest percentage of patients who showed clinical signs of autoimmunity (36.2%) was in the category of diseases of immune dysregulation, highlighting the role of lymphocyte homeostasis (Fas/FasL deficiency), immunosuppressive cytokines (IL-10 deficiency), and CTLA-4 surface expression (LRBA deficiency) in the control of autoimmunity. Here, IL10 is linked to Autoimmunity.