IL10 and lung carcinoma: Li et al. showed that administration of liposomes carrying miRNA-98 could effectively reduce the frequency of B10 cells in tumor-bearing mice and inhibit experimental tumor growth, demonstrating that IL-10-producing B cells play an important role in tumor tolerance effect, while miRNA-98 up-regulation can suppress the expression of IL-10 in B cells, which helps suppress the body's tolerance to lung cancer (62).