Also, the MFI, the average intensity of protein expression, of S100A9 in T2D was 1.5-fold higher than healthy controls (86,485 ± 30,754 compared to 57,027 ± 44,782 units) as well as for S100A12, 1.7-fold increase compared to healthy controls (244 ± 103 compared to 140 ± 69 units) (Figure 2D). Here, S100A9 is linked to type 2 diabetes mellitus.