The highest effect of hyperglycemia was gene expression of S100A9 and S100A12, in particular in pro-inflammatory M1 macrophages which are maturated with MCSF and simultaneously stimulated with IFNγ, and for S100A8 in M0 macrophages, maturated without additional stimulation (Supplementary Table 1). This evidence concerns the gene S100A9 and Hyperglycemia.