Although prednisolone (18.4 mL/h: −36.9%, 30.5 mL/h: −26.3%, 60.5 mL/h: −26.6%) and MTX (RA) (18.4 mL/h: −33.7%, 30.5 mL/h: −4.5%, 60.5 mL/h: −15.1%) reduced adhesion of RASFs to E-selectin in most patients, the results were not statistically significant (Supplement 5). This evidence concerns the gene SELE and rheumatoid arthritis.