Flow-cytometric analyses revealed significant alterations in the Lin-Thy1.2+ DN2, DN3, and DN4 subpopulations (CD25−CD44+c-Kit− DN1, CD25+CD44+c-Kit+ DN2, CD25+CD44−c-Kit− DN3, and CD25−CD44−c-Kit− DN4) isolated from the thymi of tumor-bearing mice vs. control tumor-free mice (Figures 1B,C). The gene discussed is CD44; the disease is neoplasm.