FADS2 and metabolic dysfunction-associated steatotic liver disease: The current results also showed that the gene expression related to linoleic acid (CYP2C, CYP2E1, and CYP3A4) and alpha-linolenic acid (FADS2) metabolism was changed in the NAFLD model group, whereas the expression of CYP2E1, CYP3A4, and FADS2 exhibited opposite trends following nuciferine treatment.