DRD2 and torsades de pointes: The ability of the model to detect drug-induced TdP was validated (Takahara et al., 2006) with several drugs such as the H1 antihistamine terfenadine (Monahan et al., 1990), the antipsychotic drug sertindole (Thomsen et al., 2003), and the D2 dopamine receptor antagonist sulpiride (Sugiyama et al., 2002).