CYP2J2 and cancer: CYP2J2, as mentioned above, is exclusively an epoxygenase expressed mostly in the heart, intestines, kidneys, and other tissues (Wu et al., 1996; Zeldin et al., 1997; Michaud et al., 2010; Xu et al., 2013) with increased, robust expression in multiple cancer cell lines and tissues including breast cancer (Jiang et al., 2005; Apaya et al., 2019).