In addition, Timo AIII decreased mRNA expression of MMP-9 in human pancreatic cancer cell AsPC-1 (Kim et al., 2019b) and suppressed HGF-induced MMP-9 expression in triple negative breast cancer cell MDA-MB-231 (Tsai et al., 2013). The gene discussed is MMP9; the disease is familial pancreatic carcinoma.