SLCO1B1 and myopathy: SLCO1B1*5 has been strongly associated with myopathy among the simvastatin users with an odds ratio (OR) ranging from 4.5 in heterozygotes to 16.9 in homozygotes (Link et al., 2008; Ghatak et al., 2010; Mammen and Amato, 2010; Sirtori et al., 2012; Hu et al., 2012; Rallidis et al., 2012; Sathasivam, 2012; Gong and Kim, 2013; Bhardwaj et al., 2013; Dandona, 2014; Albayda and Christopher-Stine, 2014; Maeda, 2015).