The AD group had a significantly lower score on MMSE (16.3 ± 6.1 vs. 27.7 ± 1.7) and a much higher proportion of APOE ε4 carriers (3 with 4/4, 10 with 3/4, 10 with 3/3, 1 with 2/3 vs. 0 with 4/4, 2 with 3/4, 9 with 3/3, 4 with 2/3) compared with the HC group. Here, APOE is linked to Alzheimer disease.