APOE and dementia: There were interactions among telmisartan, rosuvastatin, and APOE ε4 genotype on the changing trends in MMSE (Padjusted = 0.029), MoCA (Padjusted = 0.033), DRS (Padjusted = 0.040), CDR (Padjusted = 0.036), and IQCODE (Padjusted = 0.031) and in the incidences of dementia (Padjusted = 0.028) after adjustment for confounders.