Unfortunately, combined PET imaging did not evidence the dopaminergic alterations typical of PD showed in previous studies using mutant LRRK2 overexpressing rodents (Li et al., 2009; Dusonchet et al., 2011) or in presymptomatic subjects carrying LRRK2 mutation (Nandhagopal et al., 2008). The gene discussed is LRRK2; the disease is Parkinson disease.