WWOX and epilepsy: Previously, the clinical features of the lde/lde rats, characterized by dwarfism, postnatal lethality, epilepsy and ataxic gait, were related to a spontaneous homozygous 13-bp deletion within the exon 9 of WWOX, resulting in a premature truncation of the Wwox C-terminus (Suzuki et al., 2009).