ERG has been shown to drive the Wnt/β-catenin signalling in the context of PCa.8,36 Since we observed that levels of the Wnt targets cyclin D137 and c-Myc38 were decreased by SSO treatment, we asked whether our ERG-targeting SSOs had an effect on Wnt/β-catenin signalling. The gene discussed is ERG; the disease is posterior cortical atrophy.