CXCR3 and neoplasm: Given the rapid induction of chemokines in the infected tumors that we hypothesized would recruit CXCR3 expressing CAR T cells (Supplementary Fig. 1C), we administered VSVmIFNβ 6 h prior to adoptive transfer of third generation murine EGFRvIII CAR T cells21 to determine whether OV remodeling of the tumor could potentiate anti-tumor CAR T cell therapy (Fig. 1d).