Although qPCR analysis showed that the Ccl5 and Cxcl10 mRNAs are not robustly altered in HD-het striatal cells (Fig. 3 E and F), we cannot exclude the possibility that the Ccl5 or Cxcl10 protein levels are increased in HD-het striatal cells, compared to the controls, because they show enhanced ribosome occupancy (Fig. 3 C and D). Here, CXCL10 is linked to Huntington disease.