CXCL10 and Huntington disease: Using qPCR analysis, we confirmed that the Ccl5 and Cxcl10 mRNAs are up-regulated in HD-het and HD-homo striatal cells (Fig. 3E) and in the Q175HD-het and Q175HD-homo mouse striatum (Fig. 3F), as well as striatum of grade 3 human HD patients (Fig. 3G).