The miR-25–3 p expression in HCC monocytes was negatively correlated with PTPRO expression (r=−0.580, p<0.01) (figure 5D) and positively correlated with PD-L1 expression (r=0.495, p<0.01) (figure 5E) in human HCC monocytes. This evidence concerns the gene CD274 and hepatocellular carcinoma.