Great efforts have been made to elucidate the possible genetic background of BPD, and the current polymorphism studies mainly focused on the serotonin receptor (HTR), tryptophan hydroxylase (TPH), monoamine oxidase A (MAOA), catechol-O-methyltransferase (COMT) and dopamine transporter (DAT) genes [6–9]. The gene discussed is SLC6A3; the disease is Borderline personality disorder.