Furthermore, qRT-PCR was performed in leukemic cell lines and four primary AML blast samples to determine whether WP1130 treatment affects transcript levels of WT1. WP1130 did not affect mRNA expression of WT1 in leukemic cell lines (Fig. 3h) and four primary AML blast samples (Fig. 3i). Here, WT1 is linked to acute myeloid leukemia.