We noticed that the CD20-positive cells were mainly located at the tertiary lymphoid structures (TLS) of lung tumor tissues while CD79A-positive cells were not only located at the TLS but also randomly enriched within tumor tissues (Fig. 3b), suggesting CD20+ naïve-like B cells and plasma-like B cells might function versatile in the lung cancers. This evidence concerns the gene MS4A1 and lung carcinoma.