Beyond the full mutations, FMR1 premutation expansions (from 55 to 200 CGG repeats) have been found in children with Autism spectrum disorder (ASD; Figure 3B) [33] and in two adult-onset disorders that are Fragile X-associated tremor/ataxia syndrome (FXTAS; MIM 309550) [34] and Fragile X-associated primary ovarian insufficiency (FXPOI; MIM 311360; Figure 3B) [35]. This evidence concerns the gene FMR1 and fragile X-associated tremor/ataxia syndrome.