In ovarian and cervical cancer, miR-451 is implicated in Doxorubicin and Vinblastine resistance, as reported by Zhu et al. The main target of this miRNA is represented by P-glycoprotein, a member of the ATP-binding cassette family, which is located in the cancer cell membrane and is responsible for increased drug efflux [91]. The gene discussed is ABCB1; the disease is cervical cancer.