The adjusted ROR of the sAEs (Table 2) showed similar patterns, where the most disproportional reactions were skin toxicities (3.4; 95%CI, 2.9–4.0) including Stevens–Johnson syndrome (10.4; 95%CI, 4.0–26.9) with V+C, pyrexia (1.9; 95%CI, 1.5–2.4) and elevated CRP (2.3; 95%CI, 1.2–4.8) with D+T, and renal disorders NEC (4.1; 95%CI, 1.3–12.5) and neurological disorders (peripheral neuropathies—2.7; 95%CI, 1.2–6.1 and seizures 3.8; 95%CI, 1.8–8.0) with E+B. This evidence concerns the gene CRP and Fever.