ROR of dermatological side effects including rash, generalized rash, maculo-papular rash, erythema multiforme and rash with eosinophilia and systemic symptoms were considerably higher in V+C compared to D+T and E+B, whereas pyrexia and elevated C-reactive protein (CRP) were disproportionally higher in D+T compared to V+C and E+B. Here, CRP is linked to erythema multiforme.