In the literature, COX5B has also been proposed as a predictor of clinical outcomes in a various types of cancers, including breast cancer, glioma, gastric cancer, head and neck squamous cell carcinoma (HNSCC) and clear cell renal cell carcinoma (ccRCC) [22,26,27,28,29]. The gene discussed is COX5B; the disease is nonpapillary renal cell carcinoma.