SAFB and amyotrophic lateral sclerosis: SAFB1 is known to interact with Sam 68, hnRNP K, SRSF1, FUS and Matrin 3 (28, 36, 46) and these interaction partners have been implicated in the pathology of repeat disorders such as Fragile X‐associated Tremor/Ataxia Syndrome (FXTAS) (39), SCA10 (44) and ALS/FTD (10, 42, 46).