The identification of TSK-enriched genes implicated in EMT as well as intercellular communication with CAFs and endothelial cells raises the possibility that TSK cells induce the fibroblast and endothelial states shown to contribute to tumor progression, immunosuppression, and heterogeneity (Costa et al., 2018, Hu et al., 2012, Wagenblast et al., 2015). Here, TSKU is linked to neoplasm.