Lastly, DEPs that are typically associated with neurons (CBLN1, CBLN4, SNAP25), oligodendrocytes (MOBP, SYNE2) and astrocytes (GJA1) were detected at significantly higher levels in AF+ microglia, suggesting functional differences in either the phagocytic capacity of this subset or its ability to fully degrade ingested material. Here, GJA1 is linked to atrial fibrillation.