Although attenuated, cytotoxic CD8+ T cells increased tumour necrosis factor α (TNF‐α) secretion when exposed to autologous patient‐02' tumour cells and when compared to unstimulated PBMCs from baseline (P < .01), at day 22 during recovery after BTZ + TMZ treatment (P < .05) and at day 56 post treatment (P < .001; Figure 5K). The gene discussed is CD8A; the disease is neoplasm.