Clinically, it is characterized by the presence of constant fever, cytopenia and high levels of ferritin, interleukins (IL), granulocyte-colony stimulating factor (GCSF), interferon-γ inducible protein 10, monocyte chemoattractant protein-1, macrophage inflammatory protein 1-α and tumor necrosis factor-α.17 The gene discussed is CSF3; the disease is Fever.