We found no significant difference in tumor cell content between DCIS and IBC (Basal-like: P = 0.86, HER2: P = 0.13, LumA: P = 0.88, LumB: P = 0.19, Mann–Whitney U tests, Supplementary Fig. 1a). The gene discussed is ERBB2; the disease is ductal breast carcinoma in situ.