BHLHE40 and esophageal cancer: The name SHARP2 came from its close resemblance to the Drosophila Split-and-HAiry Related Proteins [15, 16], while DEC1 is an acronym for Differentiated in Embryonic Chondrocytes [17] (not to be confused with the tumor suppressor gene Deleted in Esophageal Cancer also called DEC1, also called Candidate Tumor Suppressor 9 or CTS9 [18]).