While differences in the expression patterns of B7H3 between the stromal and tumor cell compartments have been reported, with colorectal and pancreatic cancer showing increased positivity in stroma compared to tumor while, prostate tumors revealing a higher expression in the tumor cells over the stroma; mutually exclusive expression of B7H3 between tumors and blood vessels as observed in RB tumors have not been reported in other cancer types. This evidence concerns the gene CD276 and pancreatic neoplasm.