CD276 and neoplasm: B7H3 expression (mean IRS score ± SD) in anaplastic regions (4.63 ± 2.46; n = 11) (Fig. 7a) showed significant decrease compared to non-anaplastic regions (7.8 ± 2.82; n = 11) (Fig. 7b) of the same tumor (p = 0.0017; paired t test) (Fig. 7c).