WNT1 and Hip dysplasia: Micro-CT scans and histological sections of P60 Wnt1-Cre;Runx3f/f mice and control littermates showed that ablation of Runx3 from neural tissue resulted in flattened type hip dysplasia together with the typical cam phenotype, with extension of articular cartilage covering the cam over the femoral neck (Fig. 8b).