These endothelial cell types are relevant, as CCL2 levels are elevated in PAH patients (Itoh et al., 2006; Soon et al., 2010; Sanchez et al., 2007) and CCL2 expression is increased in endothelial cells in atherosclerotic plaques (Seino et al., 1995). The gene discussed is CCL2; the disease is pulmonary arterial hypertension.