Serum IgM levels of sixty-five pSS patients (97%) were within the reference range of normal Japanese individuals (35–220 mg/dl, Table 1) [35], while serum IgA levels of 13.4% of 9 patients (13.4%) were above the reference range (110–410 mg/dl, Table 1) [35]. The gene discussed is CD40LG; the disease is peeling skin syndrome.