SOD1 and psoriasis: Undoubtedly, the process of lipid peroxidation resulting from excessive ROS production and impairment of the antioxidative system is exacerbated in patients suffering from psoriasis, whose serum and erythrocytes show elevated content of MDA resulting from decreased β-carotene, GSH, and α-tocopherol levels as well as increased SOD activity in red blood cells [57].