ICAM1 and neoplasm: Using an elegant in vitro model consisting of a microfluidic chip covered by HUVEC endothelial cells to mimic the vascular compartment, Chen et al. revealed interactions implicating CD11b on neutrophils and ICAM-1 on cancer and endothelial cells, which favored the formation and arrest on the endothelium wall of tumor cell/neutrophil complexes [244].