However, to date, the activities of antioxidant enzymes, such as superoxide dismutase (SOD), catalase (CAT), glutathione peroxidase (GPx) and glutathione disulfide reductase (GR) that control the levels of reactive oxygen species (ROS), such as superoxide anion radical (O2•−) and hydrogen peroxide (H2O2), and are principal determinants of the redox state of cells, have not been studied in the rat model of schizophrenia induced by BSO treatment during the early postnatal life. This evidence concerns the gene CAT and schizophrenia.