SMARCA4 and lung carcinoma: Conversely, the H1299 lung cancer cell line, which carries a SMARCA4 mutation, but shows retained SMARCA2 expression (SMARCA4-/SMARCA2+), and the ovarian high-grade endometrioid adenocarcinoma cell line SKOV3 (SMARCA4+/SMARCA2+) were completely resistant to 5′-dAZAC and 100-fold less sensitive to TSA than BIN-67 (Figure 5A,B).