The 6-protein diagnostic panel consisted of FLNA, PRDX6 and ARHGDIB, associated with tumor growth, cell invasion and metastasis [36,37,38,39,40,41], GSTO1, having an antioxidant defense role (together with PRDX6) [38,41,42,43], TUBA4A, found enriched in serum exosomes from NSCLC patients [44], and the tumor suppressor CDH13 [45]. Here, TUBA4A is linked to neoplasm.