ABCA1 and Stroke: To investigate the mechanism underlying how brain ABCA1 deficiency decreases axonal myelination in the WM of the ischemic brain after stroke and how the administration of HDL3 and ApoE2 attenuate ABCA1-B/-B-induced reduction in myelination after stroke, the ultrastructural changes of WT in the CC of IBZ in the ipsilateral hemisphere were measured.