Further, 75% of lung adenocarcinomas are caused by genetic alterations promoting the RTK/RAS/RAF (receptor tyrosine kinase, rat sarcoma virus, and serine/threonine-protein kinase, respectively) signaling pathway, including Kirsten rat sarcoma (KRAS, 32%), epidermal growth factor receptor (EGFR, 11%), v-Raf murine sarcoma viral oncogene homolog B (BRAF, 7%), and mesenchymal-epithelial transition (MET) exon 14 skipping mutations (4.3%). Here, EGFR is linked to lung adenocarcinoma.